Abstract:
Objective
To investigate the short-term efficacy of embolization with sodium alginate microspheres（KMG）for treatment of hepatocellular carcinoma（HCC）.
Methods
Fifty-four patients with HCC underwent TACE/TAE with KMG. Tumor responses，complications and adverse reactions related to embolization were analyzed.
Results
TACE/TAE was successfully accomplished in all patients.The common adverse reactions after embolization including abdominal pain（36/54，66.67%），fever（30/54，55.56%），nausea and vomiting（15/54，27.78%）.No severe complication occurred.Twenty-two HCC patients also had arterioportal shunts（APS）or arteriovenous shunts（AVS）.According to modified response evaluation criteria in solid tumors（RECIST）criteria，the two months follow-up results are as follows：29.63% （16/54）with partial response，57.41% （31/54）with stable disease，and 12.96% （7/54）with progressive disease，respectively.
Conclusions
Embolization with using of KMG is a safe and feasible treatment for HCC with remarkable short-term efficacy.
Key words:
Carcinoma,hepatocellular,
Embolization,therapeutic,
Sodium alginate microspheres
Ye Sheng, Qingquan Zu, Sheng Liu, Zhengqiang Yang, Chungao Zhou, Jinguo Xia, Linbo Zhao, Yaoliang Feng, Haibin Shi. Short-term efficacy of embolization with sodium alginate microspheres in patients with hepatocellular carcinoma[J]. Chinese Journal of Interventional Radiology(Electronic Edition), 2014, 02(01): 11-14.